Selected Peer Reviewed Publications

Viral Pathogenesis

Lang W, Anderson RE, Perkins H, Grant RM, Lyman D, Winkelstein W, Royce R, Levy JA. Clinical, immunologic, and serologic findings in men at risk for acquired immunodeficiency syndrome. San Francisco Men’s Health Study. JAMA 1987;257:326-330. PMID: 3491910.

Erlich KS, Mills J, Chatis P, Mertz GJ, Busch DF, Follansbee SE, Grant RM, Crumpacker CS. Acyclovir-resistant herpes simplex virus infections in patients with acquired immunodeficiency syndrome. New England Journal of Medicine 1989;320:293-296. PMID: 2536136.

Kaur A, Grant RM, Means RE, McClure H, Feinberg M, Johnson RP. Diverse host response and outcomes following SIVmac239 infection in sooty mangabeys and rhesus macaques. Journal of Virology 1998 72(12): 9597-9611. PMC110469.

Grant RM, Piwowar EM, Katongole-Mbidde E, Muzawalu W, Rugera S, Abima J, Stramer S, Kataaha P, Jackson B. Comparison of Saliva and Serum for HIV-1 Antibody Testing in Uganda Using a Rapid Recombinant Assay. Diagnostic Laboratory and Clinical Immunology 1996 3(6):640-644. PMC170424.

McCune JM, Loftus R, Schmidt DK, Carroll P, Webster D, Swor-Yim LB, Francis IR, Gross BH, Grant RM. High Prevalence of Thymic Tissue in Adults with HIV-1 Infection. Journal of Clinical Investigation 1998 101(11):2301-2308. PMC508819.

Palacios E, Digilio L, McClure HM, Chen Z, Marx PA, Goldsmith MA, Grant RM. Parallel evolution of CCR5-null phenotypes in humans and in natural host of simian immunodeficiency virus. Current Biology 1998 8:943-946. PMID: 9707408.

Leigler TJ, Hayden MS, Lee KS, Thounaojam M, Deeks SG, Grant RM. Protease inhibitor resistant HIV-1 from patients with CD4 counts is cytopathic in activated CD4+ lymphocytes. 2001 15:179-184.

Deeks SG, Wrin T, Liegler T, Hoh R, Hayden M, Barbour JD, Hellmann NS, Petropoulos CJ, McCune JM, Hellerstein MK, Grant RM. Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia. New England Journal of Medicine 344(7):472-480, 2001. PMID: 11172188.

Bourara K, Liegler TJ,Grant RM. Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1. PLoS Pathogens 2007 3(10):e153. PMC2042017.

HIV Prevention

Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, Goicochea P, Casapia M, Guanira-Carranza JV, Ramirez-Cardich ME, Montoya-Herrera O, Fernandez T, Veloso VG, Buchbinder SP, Chariyalertsak S, Schechter M, Bekker LG, Mayer KH, Kallas EG, Amico KR, Mulligan K, Bushman LR, Hance RJ, Ganoza C, Defechereux P, Postle B, Wang F, McConnell JJ, Zheng JH, Lee J, Rooney JF, Jaffe HS, Martinez AI, Burns DN, Glidden DV. Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men. New England Journal of Medicine 2010 363(27): 2587–2599. PMC3079639.

Anderson PL, Glidden DV, Liu A, Buchbinder S, Lama JR, Guanira JV, McMahan V, Bushman LR, Casapía M, Montoya-Herrera O, Veloso VG, Mayer KH, Chariyalertsak S, Schechter M, Bekker LG, Kallás EG, Grant RM, and For the iPrEx Study Team. Emtricitabine-Tenofovir Concentrations and Pre-Exposure Prophylaxis Efficacy in Men Who Have Sex with Men. Science Translational Medicine  2012 4(151):151ra125. PMC3721979.

Grant RM, Anderson PL, McMahan V, Liu A, Amico KR, Mehrotra M, Hosek S, Mosquera C, Casapia M, Montoya O, Buchbinder S, Veloso VG, Mayer K, Chariyalertsak S, Bekker LG, Kallas EG, Schechter M, Guanira J, Bushman L, Burns DN, Rooney JF, Glidden DV for the iPrEx study team. Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study. Lancet Infect Disease 2014 Jul 22. [Epub ahead of print]. PMID: 25065857.

Drug Resistance

Grant RM, Hecht FM, Warmerdam M, Liu L, Liegler T, Petropoulos CJ, Hellmann NS, Chesney M, Busch MP, Kahn JO.   Time trends in primary HIV-1 drug resistance among persons recently infected in San Francisco. Journal of the American Medical Association 288(2):181-188, 2002. PMID: 12095382.

Grant RM, Kuritzkes DR, Johnson V, Mellors JW, Sullivan JL, Swanstrom R, D’Aquila R, Van Gorter M, Holodniy M, Lloyd RM, Reid C, Morgan G, Winslow, DL. Accuracy of the TRUGENE HIV-1 genotyping kit. Journal of Clinical Microbiology 2003 41(4):1586-93. PMC153856.

 

HIV Transmission

Winkelstein W, Lyman DM, Padian N, Grant RM, Samuel M, Wiley JA, Anderson RE, Lang W, Riggs J, Levy JA. Sexual practices and risk of infection by the human immunodeficiency virus. San Francisco Men’s Health Study. Journal of the American Medical Association 1987 257:321-325.

Angel J, Hu Y, Kravick S, Tsui R, Lee KH, Barbour J, Balaskas E, Branson BM, Delwart DL, Grant RM. Virological evaluation of the “Ottawa case” indicates no evidence for HIV-1 superinfection. AIDS 2004 18(2):331-4. PMID: 15075555.

McConnell JJ, Bragg L, Shiboski S, Grant RM. Sexual Seroadaptation: Lessons for Prevention and Sex Research from a Cohort of HIV-Positive Men Who Have Sex with Men. PLoS One. 2010 5(1):e8831. PMC2809110.

 

Mathematical Modeling

Grant RM, Buchbinder S, Cates W Jr, Clarke E, Coates T, Cohen MS, Delaney M, Flores G, Goicochea P, Gonsalves G, Harrington M, Lama JR, MacQueen KM, Moore JP, Peterson L, Sanchez J, Thompson M, Wainberg MA. Promote HIV chemoprophylaxis research, don’t prevent it. Science 2005 309(5744):2170-2171. PMID: 16195446.

Grant RM, Wiley JA, Winkelstein W. The infectivity of the human immunodeficiency virus: estimates from a cohort of homosexual men. J. Inf. Dis. 1987 156:189-193. PMID: 3474298.

Blower SM, Gershengorn HB, and Grant RM. A Tale of Two Futures: HIV and Anti-Retroviral Therapy in San Francisco. Science 2000 287:650-654. PMID: 10649998.

Gross K, Porco TC, and Grant RM. HIV-1 superinfection and viral diversity. AIDS 2004 18:1513-1520. PMID: 15238769.

Sánchez MS, Grant RM, Porco TC, Gross KL, Getz WM. A decrease in drug resistance levels of the HIV epidemic can be bad news. Bulletin of Mathematical Biology 2005 67:761-782. PMID: 15893552.

 

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